Hernández-Alcoceba, R.: search on Z-Library

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1

Human adenovirus replication in immunocompetent Syrian hamsters can be attenuated with chlorpromazine or cidofovir

Iulia Diaconu, Vincenzo Cerullo, Sophie Escutenaire, Anna Kanerva, Gerd J. Bauerschmitz, Ruben Hernandez-Alcoceba, Sari Pesonen, Akseli Hemminki

Journal:

The Journal of Gene Medicine

Year:

2010

Language:

english

File:

PDF, 341 KB

english, 2010

2

1134 AAV MEDIATED LIVER GENE THERAPY PROVIDES PROLONGED ENZYMATIC CORRECTION AND PROTECTS AGAINST INDUCED MOTOR NEUROPATHY IN ACUTE INTERMITTENT PORPHYRIA MICE

Unzu, C., Sampedro, A., Mauleon, I., Alegre, M., Beattie, S., de Salamanca, R. Enríquez, Twisk, J., Timmermans, E.J., Hernández-Alcoceba, R., Melero, I., Petry, H., González-Aseguinolaza, G., Artieda,

Journal:

Journal of Hepatology

Year:

2010

Language:

english

File:

PDF, 68 KB

english, 2010

3

New Oncolytic Adenoviruses with Hypoxia- and Estrogen Receptor-Regulated Replication

Hernandez-Alcoceba, Ruben, Pihalja, Michael, Qian, Dalong, Clarke, Michael F.

Journal:

Human Gene Therapy

Year:

2002

Language:

english

File:

PDF, 350 KB

english, 2002

4

A Novel, Conditionally Replicative Adenovirus for the Treatment of Breast Cancer That Allows Controlled Replication of E1a-Deleted Adenoviral Vectors

Hernandez-Alcoceba, Ruben, Pihalja, Michael, Wicha, Max S., Clarke, Michael F.

Journal:

Human Gene Therapy

Year:

2000

Language:

english

File:

PDF, 1.08 MB

english, 2000

5

Prolonged and inducible transgene expression in the liver using gutless adenovirus: A potential therapy for liver cancer

Lin Wang, RubÉN. HernÁndez-Alcoceba, Vijay Shankar, Maider Zabala, Stefan Kochanek, Bruno Sangro, M.Gabriela Kramer, Jesus Prieto, Cheng Qian

Journal:

Gastroenterology

Year:

2004

Language:

english

File:

PDF, 573 KB

english, 2004

6

QSAR-Derived Choline Kinase Inhibitors: How Rational can Antiproliferative Drug Design Be?

Campos, J., Nunez, M., Conejo-Garcia, A., Sanchez-Martin, R., Hernandez-Alcoceba, R., Rodriguez-Gonzalez, A., Lacal, J., Gallo, M., Espinosa, A.

Journal:

Current Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 352 KB

english, 2003

7

Gene therapy of liver cancer

Hernández-Alcoceba, Rubén, Sangro, Bruno, Prieto, Jesús

Journal:

Annals of Hepatology

Year:

2007

Language:

english

File:

PDF, 98 KB

english, 2007

8

Intrahepatic injection of adenovirus reduces inflammation and increases gene transfer and therapeutic effect in mice

Julien Crettaz, Pedro Berraondo, Itsaso Mauleón, Laura Ochoa, Vijay Shankar, Miguel Barajas, Nico van Rooijen, Stefan Kochanek, Cheng Qian, Jesús Prieto, Rubén Hernández-Alcoceba, Gloria González-Aseg

Journal:

Year:

2006

Language:

english

File:

PDF, 511 KB

english, 2006

9

Treatment of Pancreatic Cancer With an Oncolytic Adenovirus Expressing Interleukin-12 in Syrian Hamsters

Bortolanza, Sergia, Bunuales, Maria, Otano, Itziar, Gonzalez-Aseguinolaza, Gloria, Ortiz-de-Solorzano, Carlos, Perez, Daniel, Prieto, Jesus, Hernandez-Alcoceba, Ruben

Journal:

Molecular Therapy

Year:

2009

Language:

english

File:

PDF, 2.63 MB

english, 2009

10

110. Safety and Antitumor Effect of Oncolytic and Helper-Dependent Adenoviruses Expressing Interleukin-12 Variants in a Hamster Pancreatic Cancer Model

Poutou, Joanna, Bunuales, Maria, Gonzalez, Manuela, Garcia-Aragoncillo, Eva, Quetglas, Jose I., Casado, Raquel, Bravo-Perez, Carlos, Alzuguren, Pilar, Hernandez-Alcoceba, Ruben

Journal:

Molecular Therapy

Year:

2015

Language:

english

File:

PDF, 298 KB

english, 2015

11

53 Regulation of interleukin 12 expression in the liver for the treatment of hepatic tumors

M. Zabala, L. Wang, R. Hernandez-Alcoceba, W. Hillen, C. Qian, J. Prieto, M.G. Kramer

Journal:

Journal of Hepatology

Year:

2004

Language:

english

File:

PDF, 57 KB

english, 2004

12

652. In Vivo Evaluation of an Oncolytic Adenovirus Regulated by Hypoxia

Bortolanza, Sergia, Prieto, Jesus, Alzuguren, Pilar, Carro, Elvira, Hernandez-Alcoceba, Ruben

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 82 KB

english, 2006

13

LUMO energy of model compounds of bispyridinium compounds as an index for the inhibition of choline kinase

Joaquı́n Campos, Marı́a del Carmen Núñez, Vicente Rodrı́guez, Antonio Entrena, Rubén Hernández-Alcoceba, Félix Fernández, Juan Carlos Lacal, Miguel A Gallo, Antonio Espinosa

Journal:

European Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 135 KB

english, 2001

14

Recent advances in oncolytic virus design

Rubén Hernández-Alcoceba

Journal:

Clinical and Translational Oncology

Year:

2011

Language:

english

File:

PDF, 185 KB

english, 2011

15

Deletion of the E3-6.7K/gp19K region reduces the persistence of wild-type adenovirus in a permissive tumor model in Syrian hamsters

Bortolanza, S, Bunuales, M, Alzuguren, P, Lamas, O, Aldabe, R, Prieto, J, Hernandez-Alcoceba, R

Journal:

Cancer Gene Therapy

Year:

2009

Language:

english

File:

PDF, 293 KB

english, 2009

16

Improvement of Adeno-Associated Virus-Mediated Liver Transduction Efficacy by Regional Administration in Macaca fascicularis

Zabaleta, Nerea, Salas, David, Paramo, Maria, Hommel, Mirja, Sier-Ferreira, Valerie, Hernandez-Alcoceba, Ruben, Prieto, Jesus, Bilbao, Jose I., Gonzalez-Aseguinolaza, Gloria

Journal:

Human Gene Therapy Clinical Development

Year:

2017

Language:

english

File:

PDF, 999 KB

english, 2017

17

Improvement of gene therapy for Wilson’s disease

Murillo-Sauca, O., Moreno-Luqui, D., Gazquez, C., Navarro-Blasco, I., Hernández-Alcoceba, R., González-Aseguinolaza, G.

Journal:

Journal of Hepatology

Year:

2017

Language:

english

File:

PDF, 87 KB

english, 2017

18

Danio Rerio as Model Organism for Adenoviral Vector Evaluation

GulÃas, Paola, Guerra-Varela, Jorge, Gonzalez-Aparicio, Manuela, Ricobaraza, Ana, Vales, Africa, Gonzalez-Aseguinolaza, Gloria, Hernandez-Alcoceba, RubÃ©n, SÃ¡nchez, Laura

Journal:

Year:

2019

File:

PDF, 1.70 MB

2019

19

Antitumor Activity of an Oncolytic Adenoviral-CD40 Ligand (CD154) Transgene Construct in Human Breast Cancer Cells

Gomes, E. M., Rodrigues, M. S., Phadke, A. P., Butcher, L. D., Starling, C., Chen, S., Chang, D., Hernandez-Alcoceba, R., Newman, J. T., Stone, M. J., Tong, A. W.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 500 KB

english, 2009

20

Intrapulmonary Expression of Macrophage Inflammatory Protein 1 (CCL3) Induces Neutrophil and NK Cell Accumulation and Stimulates Innate Immunity in Murine Bacterial Pneumonia

Zeng, X., Moore, T. A., Newstead, M. W., Hernandez-Alcoceba, R., Tsai, W. C., Standiford, T. J.

Journal:

Infection and Immunity

Year:

2003

Language:

english

File:

PDF, 756 KB

english, 2003

21

Novel tumour-specific promoters for transcriptional targeting of hepatocellular carcinoma by herpes simplex virus vectors

Pelagia Foka, Aldo Pourchet, Ruben Hernandez-Alcoceba, Polyxeni P. Doumba, George Pissas, Vlassis Kouvatsis, Georgia Dalagiorgou, Dorothea Kazazi, Peggy Marconi, Mariagiovanna Foschini, Roberto Manser

Journal:

The Journal of Gene Medicine

Year:

2010

Language:

english

File:

PDF, 466 KB

english, 2010

22

An oncolytic adenovirus controlled by a modified telomerase promoter is attenuated in telomerase-negative cells, but shows reduced activity in cancer cells

S. Bortolanza, C. Qian, M. G. Kramer, C. Gomar, J. Prieto, F. Farinati, R. Hernandez-Alcoceba

Journal:

Journal of Molecular Medicine

Year:

2005

Language:

english

File:

PDF, 429 KB

english, 2005

23

357 A potential therapy for liver metastasis mediated by the inducible expression of interleukin-12 (IL-12) using gutless adenoviral vector

R. Hernandez-Alcoceba, L. Wang, S.G. Shankar, M. Zabala, S. Kochanek, B. Sangro, M.G. Kramer, J. Prieto, C. Qian

Journal:

Journal of Hepatology

Year:

2004

Language:

english

File:

PDF, 63 KB

english, 2004

24

Visualization of the therapeutic efficacy of a gene correction approach in Wilson's disease by Laser-ablation inductively coupled mass spectrometry

Moreno, Daniel, Murillo, Oihana, Gazquez, Cristina, Hernandez-Alcoceba, Ruben, Uerlings, Ricarda, Gonzalez-Aseguinolaza, Gloria, Weiskirchen, Ralf

Journal:

Journal of Hepatology

Year:

2018

Language:

english

File:

PDF, 2.54 MB

english, 2018

25

Gene therapy of liver cancer

Hernandez-Alcoceba, Ruben

Journal:

World Journal of Gastroenterology

Year:

2006

Language:

english

File:

PDF, 715 KB

english, 2006

26

Evaluation of a new dual-specificity promoter for selective induction of apoptosis in breast cancer cells

Hernandez-Alcoceba, Ruben, Pihalja, Michael, Nunez, Gabriel, Clarke, Michael F

Journal:

Cancer Gene Therapy

Year:

2001

Language:

english

File:

PDF, 1.04 MB

english, 2001

27

Choline kinase inhibitors as a novel approach for antiproliferative drug design

Hernández-Alcoceba, Rubén, Saniger, Luisa, Campos, Joaquín, Núñez, M Carmen, Khaless, Fouad, Gallo, Miguel Angel, Espinosa, Antonio, Lacal, Juan Carlos

Journal:

Year:

1997

Language:

english

File:

PDF, 605 KB

english, 1997

28

Gene therapy of liver diseases

Prieto, Jesus, Qian, Cheng, Hernandez-Alcoceba, Ruben, Gonzalez-Aseguinolaza, Gloria, Mazzolini, Guillermo, Sangro, Bruno, Kramer, M Gabriela

Journal:

Expert Opinion on Biological Therapy

Year:

2004

Language:

english

File:

PDF, 262 KB

english, 2004

29

Human Adenovirus Replicates in Immunocompetent Models of Pancreatic Cancer in Syrian Hamsters

Bortolanza, Sergia, Alzuguren, Pilar, Buñuales, Maria, Qian, Cheng, Prieto, Jesus, Hernandez-Alcoceba, Ruben

Journal:

Human Gene Therapy

Year:

2007

Language:

english

File:

PDF, 488 KB

english, 2007

30

Oxaliplatin in combination with liver-specific expression of interleukin 12 reduces the immunosuppressive microenvironment of tumours and eradicates metastatic colorectal cancer in mice

Gonzalez-Aparicio, M., Alzuguren, P., Mauleon, I., Medina-Echeverz, J., Hervas-Stubbs, S., Mancheno, U., Berraondo, P., Crettaz, J., Gonzalez-Aseguinolaza, G., Prieto, J., Hernandez-Alcoceba, R.

Journal:

Year:

2011

Language:

english

File:

PDF, 729 KB

english, 2011

31

Gene therapy approaches against cancer using in vivo and ex vivo gene transfer of interleukin-12

Hernandez-Alcoceba, Ruben, Poutou, Joanna, Ballesteros-Briones, María Cristina, Smerdou, Cristian

Journal:

Year:

2016

Language:

english

File:

PDF, 1.70 MB

english, 2016

32

Lethality in an anti-angiogenic tumor gene therapy model upon constitutive but not inducible expression of the soluble vascular endothelial growth factor receptor 1

Vijayshankar Ganesh Sivanandam, Sam Laurel Stephen, Ruben Hernandez-Alcoceba, Pilar Alzuguren, Maider Zabala, Nico van Rooijen, Cheng Qian, Irina Berger, Marie-Luise Gross, Jesus Prieto, Stefan Kochan

Journal:

The Journal of Gene Medicine

Year:

2008

Language:

english

File:

PDF, 283 KB

english, 2008

33

Evaluation of hepatocellular carcinoma models for preclinical studies

M. Gabriela Kramer, Ruben Hernandez-Alcoceba, Cheng Qian, Jesus Prieto

Journal:

Drug Discovery Today: Disease Models

Year:

2005

Language:

english

File:

PDF, 269 KB

english, 2005

34

Immunochemotherapy against colon cancer by gene transfer of interleukin-12 in combination with oxaliplatin

Hernandez-Alcoceba, Ruben, Berraondo, Pedro

Journal:

Year:

2012

Language:

english

File:

PDF, 1.14 MB

english, 2012

35

Gene therapy of liver cancer: an update

G. Gonzalez-Aseguinolaza, J. Prieto, R. Hernandez-Alcoceba

Journal:

Journal africain du cancer / African Journal of Cancer

Year:

2011

File:

PDF, 159 KB

2011

36

[383] INTRAHEPATIC INJECTION OF ADENOVIRUS REDUCES INFLAMMATION AND INCREASES GENE TRANSFER AND THERAPEUTIC EFFECT IN MICE

J. Crettaz, P. Berraondo, I. Mauleon, L. Ochoa, V. Shankar, M. Barajas, N. van Rooijen, S. Kochanek, C. Qian, J. Prieto, R. Hernandez-Alcoceba, G. Gonzalez-Aseguinolaza

Journal:

Journal of Hepatology

Year:

2007

Language:

english

File:

PDF, 252 KB

english, 2007

37

Combining virotherapy and angiotherapy for the treatment of breast cancer

Bazan-Peregrino, M, Sainson, R C A, Carlisle, R C, Thoma, C, Waters, R A, Arvanitis, C, Harris, A L, Hernandez-Alcoceba, R, Seymour, L W

Journal:

Cancer Gene Therapy

Year:

2013

Language:

english

File:

PDF, 1.98 MB

english, 2013

38

Safety and antitumor effect of oncolytic and helper-dependent adenoviruses expressing interleukin-12 variants in a hamster pancreatic cancer model

Poutou, J, Bunuales, M, Gonzalez-Aparicio, M, Garcia-Aragoncillo, E, Quetglas, J I, Casado, R, Bravo-Perez, C, Alzuguren, P, Hernandez-Alcoceba, R

Journal:

Year:

2015

Language:

english

File:

PDF, 1.83 MB

english, 2015

39

Inhibition of adenovirus infection by mifepristone

Marrugal-Lorenzo, José A., Serna-Gallego, Ana, González-González, Loreto, Buñuales, Maria, Poutou, Joanna, Pachón, Jerónimo, Gonzalez-Aparicio, Manuela, Hernandez-Alcoceba, Ruben, Sánchez-Céspedes, Ja

Journal:

Antiviral Research

Year:

2018

Language:

english

File:

PDF, 1.24 MB

english, 2018

40

Growth Inhibition of Human Multiple Myeloma Cells by an Oncolytic Adenovirus Carrying the CD40 Ligand Transgene

Fernandes, M. S., Gomes, E. M., Butcher, L. D., Hernandez-Alcoceba, R., Chang, D., Kansopon, J., Newman, J., Stone, M. J., Tong, A. W.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 543 KB

english, 2009

41

Brain copper storage after genetic long-term correction in a mouse model of Wilson disease

Uerlings, Ricarda, Moreno, Daniel, Murillo, Oihana, Gazquez, Cristina, Hernández-Alcoceba, Rubén, González-Aseguinolaza, Gloria, Weiskirchen, Ralf

Journal:

Neurology: Genetics

Year:

2018

Language:

english

File:

PDF, 640 KB

english, 2018

42

The Ras family of GTPases in cancer cell invasion

R. Hernández-Alcoceba, L. del Peso, J. C. Lacal*

Journal:

Cellular and Molecular Life Sciences

Year:

2000

Language:

english

File:

PDF, 138 KB

english, 2000

43

Self-inactivating helper virus for the production of high-capacity adenoviral vectors

Gonzalez-Aparicio, M, Mauleon, I, Alzuguren, P, Bunuales, M, Gonzalez-Aseguinolaza, G, San Martín, C, Prieto, J, Hernandez-Alcoceba, R

Journal:

Year:

2011

Language:

english

File:

PDF, 545 KB

english, 2011

44

Modulation of phospholipase D by hexadecylphosphorylcholine: a putative novel mechanism for its antitumoral activity

Lucas, Luisa, Hernández-Alcoceba, Rubén, Penalva, Verónica, Lacal, Juan Carlos

Journal:

Year:

2001

Language:

english

File:

PDF, 181 KB

english, 2001

45

Modulation of phospholipase d by hexadecylphosphorylcholine: a putative mechanism for its antitumoral activity

L. Lucas, R. Hernandez-Alcoceba, V. Penalva, J. Lacal

Journal:

European Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 185 KB

english, 2001

46

Rho proteins induce metastatic properties in vivo

Peso, Luis del, Hernández-Alcoceba, Rubén, Embade, Nieves, Carnero, Amancio, Esteve, Pilar, Paje, Carmen, Lacal, Juan Carlos

Journal:

Year:

1997

Language:

english

File:

PDF, 1.23 MB

english, 1997

47

Identification of Replication-competent HSV-1 Cgal+ Strain Signaling Targets in Human Hepatoma Cells by Functional Organelle Proteomics

Santamaria, E., Mora, M. I., Potel, C., Fernandez-Irigoyen, J., Carro-Roldan, E., Hernandez-Alcoceba, R., Prieto, J., Epstein, A. L., Corrales, F. J.

Journal:

Molecular & Cellular Proteomics

Year:

2009

Language:

english

File:

PDF, 592 KB

english, 2009

48

Cytokines for the treatment of gastrointestinal cancers: clinical experience and new perspectives

Hernandez-Alcoceba, Ruben, Sangro, Bruno, Berraondo, Pedro, Gonzalez-Aseguinolaza, Gloria, Prieto, Jesus

Journal:

Expert Opinion on Investigational Drugs

Year:

2013

Language:

english

File:

PDF, 661 KB

english, 2013

49

Gene therapy strategies for the treatment of cancer. A review

Rubén Hernández-Alcoceba

Journal:

Clinical and Translational Oncology

Year:

2000

Language:

english

File:

PDF, 469 KB

english, 2000

50

273 PROPERTIES AND LIMITATIONS OF MONOCYTES AND CANCER CELLS AS CARRIERS FOR REPLICATION-COMPETENT ADENOVIRAL VECTORS IN LIVER METASTASES OF PANCREATIC CANCER

E. Garcia-Aragoncillo, M. Bunuales, R. Casado, S. Bortolanza, J. Prieto, R. Hernandez-Alcoceba

Journal:

Journal of Hepatology

Year:

2012

Language:

english

File:

PDF, 53 KB

english, 2012

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